Toxicological and pharmacokinetic properties of sucralose-6-acetate and its parent sucralose: in vitro screening assays
(www.tandfonline.com)https://www.tandfonline.com/doi/full/10.1080/10937404.2023.2213903"sucralose-6-acetate is genotoxic. The mechanism of action was classified as clastogenic (produces DNA strand breaks) "
"Sucralose-6-acetate significantly increased the expression of genes associated with inflammation, oxidative stress, and cancer"
"sucralose-6-acetate and sucralose both impaired intestinal barrier integrity."
"the toxicological and pharmacokinetic findings for sucralose-6-acetate raise significant health concerns regarding the safety and regulatory status of sucralose itself."
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