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37 comments block


[ - ] pickingrinninspittin 7 points 4 hoursMay 23, 2025 11:46:46 ago (+7/-0)

Any video with fast cuts, radical claims, and epic sweeping music goes automatically high up on the "Probably Bullshit" list.

[ - ] Belfuro 2 points 1 hourMay 23, 2025 14:03:54 ago (+2/-0)

Any common public knowledge since ww2 is going to be a lie.

Smoking causes lung cancer? Then why has smoking rates fallen off a cliff while lung cancer rates remain just as high?

As for nicotine being addictive. Well i grew and smoked my own tobacco last year as some of you know.
Anecdotally, zero signs of addiction.

Meanwhile nicotine has long known to be a neuro protector. Ive reversed my memory loss and inability to learn new things.

Now admittingly i also went human diet rather than judeo-nigger shit food.
Aka carnivore/keto

[ - ] SocksOnCats 2 points 4 hoursMay 23, 2025 11:37:42 ago (+2/-0)

Alright.

Can any goats out here with any kind of medical or scientific background verify what's being claimed here?

Is nicotine actually NOT addictive?

[ - ] CHIRO 9 points 4 hoursMay 23, 2025 11:46:34 ago (+9/-0)*

It is addictive. Any smoker will be familiar with the impacts of nicotine on the GI tract and smooth muscle tissue. This is because nicotine is an acetylcholine receptor agonist. In other words, it can substitute for acetylcholine as a neurotransmitter. After a sufficient amount of time of sustained nicotine use, your daily intake becomes integrated into your body's chemistry.

People will often talk about the unique difficulty of smoking cessation. They're right. The reason is that you have an adjustment period where your body has to recognize via negative feedback that it needs to upregulate its acetylcholine receptors to adapt to the absence of nicotine (that you'd been providing it every day for X years). Acetylcholine is probably the most abundant and universal neurotransmitter in your body.

This is why removing nicotine, at least initially, for addicts results in that awful "shut down" feeling. It's not just psychological. Your whole nervous system was impacted by the gas you were giving it. So, right away, removing it is like trying to heat a room the same size with half the wood. Another good analogy is to think of the potent urges to light up as certain "labor unions" in your body "suing" your brain, like they had a contract for the provision of a chemical. In the case of nicotine, it's pretty much your whole body that's unionized. The withdrawal is not as physically acute as getting off stronger narcotics. The difference is that the labor union that's suing is larger so the impulse to smoke is strong and constant and lasts for an absurd amount of time. You can suddenly be overcome with a powerful urge to smoke weeks and months after ceasing.

In principle, if you know you are dealing with a direct neurotransmitter substitute (anything capable of interacting directly with your nervous system), you are dealing with something potentially addictive. That's just how we are built.

Anybody who tells you nicotine is non-addictive is a moron.

[ - ] Aze 3 points 2 hoursMay 23, 2025 13:13:07 ago (+3/-0)

That was an amazing breakdown. Thank you Chiro.

[ - ] rzr97 1 point 1 hourMay 23, 2025 14:19:50 ago (+1/-0)*

...and just like damn near every addictive thing out there, it's dead simple to get off of. Some like serotonin reuptake inhibitors and a few others take longer but it's the same thing.

To get off of anything addictive, just start taking a little less increasingly over time. That's it. It's not a great mystery. I've been addicted to many things and this is simply how it's done. Meh. No big deal at all.

If you know this and can't get off of something addictive you're probably gay. Ok, I made that last part up but still...it's not that difficult. Maybe the worst is food since you have to eat.

Edit: I guess the truth is I'm probably describing physical dependence and not mental addiction.

[ - ] Master_Foo 5 points 4 hoursMay 23, 2025 11:47:58 ago (+5/-0)*

Nicotine is more addictive than heroin.
There's a reason why almost every smoker desperately wants to quit, paying $400/month, to give themselves lung cancer, and emphysema, and can't quit for more than half a day.

There is a simpler answer here:
Jews lie.

[ - ] rzr97 0 points 1 hourMay 23, 2025 14:21:49 ago (+0/-0)*

To get off of anything addictive, just start taking a little less increasingly over time. That's it. It's not a great mystery. I've been addicted to many things and this is simply how it's done. Meh. No big deal at all.

Edit: I guess the truth is I'm probably describing physical dependence and not mental addiction.

[ - ] Master_Foo 0 points 1 hourMay 23, 2025 14:41:27 ago (+0/-0)

You expect NPCs to have the willpower to do that?

[ - ] rzr97 0 points 1 hourMay 23, 2025 14:46:57 ago (+0/-0)

Well I guess the truth is I'm probably describing physical dependence and not mental addiction.

[ - ] KtownKracker 0 points 1 hourMay 23, 2025 14:29:01 ago (+0/-0)

Sugar is right up there too.

[ - ] PostWallHelena 1 point 4 hoursMay 23, 2025 11:48:49 ago (+1/-0)

Of course its addictive.

[ - ] protodonata 1 point 3 hoursMay 23, 2025 12:09:58 ago (+1/-0)

https://pmc.ncbi.nlm.nih.gov/articles/PMC9871277/

You can find plenty of studies to read on the benefits of nicotine. If you just "Google" it though they are pretty hard to find because most report on tobacco products, not nicotine alone. Need to search pubmed/ncbi/Google scholar etc.

My personal experience is that nicotine itself isn't addictive but the habit in which you take the nicotine is, you repeat something enough you're training your body for a dopamine hit. If you secretly removed the nicotine from a persons vape, they would still get placebo effect.

I smoked for about a year when I was a teen, tried to go for a mountain bike ride and felt it in my lungs, quit cold turkey that day.

Didn't pick nicotine back up until started working construction many years later. Tobacco based chew. Got grossed out by that and quit cold turkey.

10 years later after no nicotine use the nicotine salt pouches showed up and gave them a try. Been on and off with those.

I'm healthy, I workout 5 days a week alternating lifting and running. There is a a difference on and off nicotine. But I also feel like too much is a bad thing as with anything. I feel like there is a neural burnout when taken too long. If you would really like the benefits of nicotine but are worried about the addiction I would cycle it. 2 weeks on 2 weeks off. Or change the method in which you get nicotine, patch one week/ gum the next/ pouches the next. I don't recommend vaping due to oils and contamination.

Habits are hard to form and hard to break, the mind doesn't like change, if you don't get it used to anything it won't miss it either.

[ - ] Sector2 0 points 3 hoursMay 23, 2025 12:42:47 ago (+0/-0)

https://www.northerner.com/us/the-northerner/research/how-many-nicotine-pouches-a-day

"Higher nicotine content means fewer pouches may be needed per day for the desired effect."

What's the desired effect you've noticed? I tried some of those stick-on patches, and nothing happened. If something does happen with nicotine, what is it?

[ - ] rzr97 1 point 1 hourMay 23, 2025 14:22:41 ago (+1/-0)*

To get off of anything addictive, just start taking a little less increasingly over time. That's it. It's not a great mystery. I've been addicted to many things and this is simply how it's done. Meh. No big deal at all.

Edit: I guess the truth is I'm probably describing physical dependence and not mental addiction.

[ - ] Sector2 0 points 55 minutesMay 23, 2025 15:08:28 ago (+0/-0)

I'm skeptical of 'addiction' because if you want to stop doing or taking something you just stop. You have to want to though.

[ - ] PostWallHelena 0 points 2 hoursMay 23, 2025 13:16:02 ago (+0/-0)

If something does happen with nicotine, what is it?

Relief from nicotine withdrawal 🤣

I used the patches for awhile when quitting cigarettes. Just as with cigarettes, heavy excercise becomes difficult. It probably curbs appetite though I didn’t notice that particularly since Id been addicted for a long time. I noticed pain in the muscles of my arm where I put the patches. I believed the nicotine pooled in my arm causing extreme vascular constriction in that part of the body. If I left the patches on over night I would wake up sweating. I began to cut the patches up into smaller patches and put them on separate limbs to reduce the pain issue. When I stepped down to lower doses I began the nervous habit of rubbing my patch to speed nicotine release. Its really toxic stuff. Im not surprised people get heart attacks from it.

I may as well mention here that there was solid evidence that nicotine users had lower incidence of covid and less severe covid because the nicotine binds to the ACE2 receptor, blocking the SARS CoV2 virus.

[ - ] Sector2 0 points 2 hoursMay 23, 2025 13:43:49 ago (+0/-0)

Maybe the dose was too low. Even with two patches, it was less than 2 milligrams per hour. You're probably right about just being for withdrawal relief.

[ - ] rzr97 0 points 1 hourMay 23, 2025 14:24:04 ago (+0/-0)*

To get off of anything addictive, just start taking a little less increasingly over time. That's it. It's not a great mystery. I've been addicted to many things and this is simply how it's done. Meh. No big deal at all.

Edit: I guess the truth is I'm probably describing physical dependence and not mental addiction.

[ - ] Master_Foo 0 points 1 hourMay 23, 2025 14:48:37 ago (+0/-0)

I tried a nicotine pouch once.
Gave me the craziest fucking dreams of my life.

We're talking about hunting/running away from dinosaurs with my Saturday morning cartoon heroes kind of crazy.

ProTip: If you are hiding in a basement from T-Rex, Casey Jones is useless.
When you are picking your team mates, go with Optimus Prime.

[ - ] BushChuck5002 1 point 3 hoursMay 23, 2025 12:19:35 ago (+2/-1)

In my experience it depends how the nicotine is consumed.

I've smoked cigarettes, chewed, snuffed, vaped, and cigars.

Snuff, chew, and cigars barely produce any addiction pattern for me, at all. Most days I will have a cigar, but not every day.

Whereas cigarettes, and vape are highly addictive.

From what i can see the primary difference is absorption of nicotine through mucus membrane vs alveoli.

There's also the matter that chew, snuff, and cigars are essentially fermented tobacco, and cigarettes/vape are highly processed.

[ - ] big_fat_dangus 0 points 2 hoursMay 23, 2025 13:16:27 ago (+0/-0)

The addict in the depths of denial.

[ - ] BushChuck5002 0 points 1 hourMay 23, 2025 14:33:58 ago (+1/-1)

lol, at this fat drunkard calling anyone else an addict.

Tell us more, retard.

[ - ] big_fat_dangus 0 points 1 hourMay 23, 2025 14:57:18 ago (+0/-0)

Tell us more about why you whine and cry over muh cigars daily, bald cuck.

[ - ] Crackinjokes 1 point 3 hoursMay 23, 2025 13:02:46 ago (+1/-0)

[ - ] Crackinjokes 1 point 3 hoursMay 23, 2025 12:56:31 ago (+1/-0)

This is wild. I want to see the study about the glioblastemas. For those who don't know that's brain cancer.

[ - ] Doglegwarrior 0 points 2 hoursMay 23, 2025 13:04:14 ago (+0/-0)

I smoke a ton of cigars 3 a day... I take a trucks as a side job can't smoke. I have zero withdrawal from not smoking in my opinion nicotine for me is not addictive at all... just my 3 cents

[ - ] PostWallHelena 0 points 3 hoursMay 23, 2025 12:05:10 ago (+0/-0)

Nicotine is a means of slavery just like booze and caffeine and weed and heroin. The aristocracy of the colonial powers realized they could grow addictive substances like nicotine cheaply, using nigger labor and then addict Europeans and live off their addictions. How many poor people have live sick and die young so that these parasites can live like kings?

Nicotine, like booze and caffeine, has a few distinct “medicinal” benefits but for the average person, it has no healthy purpose and will only turn you into a zombie addict and make you fork all your money over to jews. I smoked for 15 years. It sucked. Now I have to worry about lung cancer for the rest of my life. I have a friend who can’t quit and has chronic clots because of it (DVT). My aunt got bladder cancer and died because of it. Its bad, even if you don’t smoke it. Dont believe these stupid promotions.

[ - ] BushChuck5002 0 points 3 hoursMay 23, 2025 12:23:55 ago (+1/-1)

[ - ] PostWallHelena 0 points 2 hoursMay 23, 2025 13:18:07 ago (+0/-0)

How does that link prove Im incorrect? I said the limited medicinal benefits do not outweigh the health risks that lead to high mortality. Your link does not contradict me.

[ - ] deleted 0 points 1 hourMay 23, 2025 14:54:04 ago (+0/-0)

deleted

[ - ] rzr97 0 points 1 hourMay 23, 2025 14:24:45 ago (+0/-0)*

To get off of anything addictive, just start taking a little less increasingly over time. That's it. It's not a great mystery. I've been addicted to many things and this is simply how it's done. Meh. No big deal at all.

Edit: I guess the truth is I'm probably describing physical dependence and not mental addiction.

[ - ] PostWallHelena 0 points 1 hourMay 23, 2025 14:29:06 ago (+0/-0)

If it was that easy everyone would do it. Addictive substances hack your biology and make you a slave to the parasites that sell them. Similar to banking and insurance and socialism. But Im sure you find it easy to avoid any of those things.

[ - ] rzr97 0 points 1 hourMay 23, 2025 14:31:52 ago (+0/-0)

It TRULY is that easy. Most people don't even know how to do it. I'm curious why you think it's not that easy. All you're doing is the same process that made you become an addict but in reverse.

What you're doing is slowly increasing your receptors sensitivity to whatever the addiction is and increasing your receptor density in some cases. It's literally the best way to quit anything.

[ - ] PostWallHelena 0 points 1 hourMay 23, 2025 15:00:18 ago (+0/-0)

Well lets see. I quit pot. I quit cigarettes. I quit booze. I quit caffeine. I quit junk food. So Ive had some experience with it. Its not easy. Its hard. And its emotionally painful. And physically stressful. I have seen people kill themselves because they couldn’t stop their addictions. You’re just being facile. This shit wouldn’t be a trillion dollar industry if it was easy to stop.

[ - ] rzr97 0 points 1 hourMay 23, 2025 14:48:09 ago (+0/-0)

Well I guess the truth is I'm probably describing physical dependence and not mental addiction.

I'll edit my comments.

[ - ] PostWallHelena 0 points 58 minutesMay 23, 2025 15:05:12 ago (+0/-0)

Theres no difference. Mental or emotional dependence is indeed physical . The major problem caused by addiciton is emotional disregulation. Even “non-physical” types of dependence like porn addiction and gambling do this and it is neuro-chemical (i.e. physical) in nature.

[ - ] rzr97 0 points 34 minutesMay 23, 2025 15:29:05 ago (+0/-0)*

There is a difference unless you're talking about reward pathways being physical which I suppose that's correct--dopamine rewards, etc. Dependence though is more than just reward pathways.

Dependence is primarily physical, while addiction is primarily mental and behavioral.

• Dependence means your body has adapted to the drug. You see tolerance and predictable withdrawal if you stop suddenly.
• Addiction means you feel cravings, lose control, and keep using despite harm. It can exist with or without strong physical withdrawal.
• Many people with addiction also have dependence, but you can be dependent without being addicted (e.g., a patient taking opioids exactly as prescribed).
• Manage dependence by tapering or substituting the drug to avoid withdrawal.
• Manage addiction with behavioral therapy, social support, and (when appropriate) medication-assisted treatments like buprenorphine or naltrexone.

Above is o3s take. I think that's correct.

When I quit anything I just taper. Try it with caffeine. Start slowly building up your caffeine intake over the course of a few months until you're having to take more and more. If you quit suddenly you'll get sick. If you just slowly decrease the amounts, you'll be fine. If it's some psychological dependence in habit or just cravings or whatever well that boils down to possibly will power for most. I can easily quit caffeine for instance. I could do this cycle year round and be perfectly fine going on and off. Supposedly the new glp-1s help with that kind of addiction.