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Many mechanisms within cells and organs are too complex to have originated by random mutations and gradual change. They require all the interdependent parts to be functioning at once. Multiple parts working in tandem via complex chemical processes cannot have resulted from mutations. It's the same idea as your computer having many different parts. Obviously it was designed as an integrated system to function properly, including the codes that enable the computer to process information. The analogy is completely relevant and compares to the DNA code within every cell. The vast majority of these rare mutations are harmful or even fatal. Science hasn't even explained how the first cell with all it's complex functions formed from a puddle and was able to reproduce. No change from one species to another has ever been observed in the fossil record. A cat remains a cat, a dog a dog, a finch a finch, etc. Variations within species can be explained by differing environments and natural selection, but they remain within their species.