These are some of the biggest Fallout 4 mods in existence right now. In the wake of Fallout London's delay, we have some time before we see the game come out. TeamFOLON has their work cut out for them updating the entirety of Fallout London to fit with the new Fallout 4 Next Gen Update and the new version of Fallout 4 Script Extender. Suffice to say, I think it's possible we will be waiting a while; however while we wait let's go over some of the biggest mods being made right now for Fallout 4. These mods, with the exception of Fallout Miami, are all Total Conversion mods.
What is a Total Conversion Mod? A Total Conversion (or TC for short) mod is a mod that seeks to completely change the way a game is played, down to it's core mechanics. Differing from an Overhaul, which aims to rebalance and reshape the core gameplay while not changing too much about the game itself, a TC can place the player in a brand new setting, with a brand new story and characters and quests.
Fallout 4 Quest Mods have been around for some time to this point, but these go even beyond Quest Mods; these are more akin to playing a completely brand new Fallout game experience. Each team is committed to making the most Fallout-friendly TC mod they can, constantly reviewing and comparing their output with the previously established Fallout Lore, to ensure their creation fits seamlessly within the Wasteland. Some of these are brand new experiences, and there are some on this list that are Fallout Remakes! Such as remakes of the Classic Fallout RPGs, Fallout 1 and 2, and a Fallout New Vegas remake!
CORRECTIONS: via @uuntiedshoelace for Fallout: Miami "Hi, Fallout: Miami dev here! Thanks for covering our mod, I just wanted to address a couple of things so there’s no confusion. We have three companions (not two) and we also do have a canon faction that appears - the Enclave is a main faction in Miami."
There doesn't seem to be anything here yet