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he was a very good piano man and composer and look what i found....
can DNA damage cause this condition?

ChatGPT said:


1. DNA Damage and Aging
Cumulative DNA damage is a hallmark of aging and contributes to cellular senescence, neurodegeneration, and loss of homeostatic regulation in brain tissue.

This damage can affect ependymal cells (which line the brain’s ventricles and are involved in CSF movement) and glial cells, potentially disrupting normal CSF dynamics.

2. Impact on CSF Absorption and Brain Structure
If DNA damage contributes to chronic inflammation, vascular changes, or white matter degeneration, it may influence the brain's ability to absorb and regulate CSF — indirectly promoting conditions like NPH.

3. Neurodegenerative Link
There is some overlap in symptoms and pathology between iNPH and neurodegenerative diseases like Alzheimer’s and Parkinson’s, where DNA damage and mitochondrial dysfunction are more clearly implicated.

Bottom Line:
DNA damage is not a known primary cause of NPH, but it may contribute to the aging-related processes that predispose individuals to iNPH. More research is needed to clarify these connections.* If you're considering the role of genetic or molecular mechanisms in NPH, it's currently more a matter of hypothesis and indirect association than direct causation.

he is fucked