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Not via their official IDE at least, it is absolute dogshit. I haven't checked, but the first thing I'd want to establish is how the underlying toolchain works, get my own processes working for compile and flash. Learn how its memory addressing is mapped.

I'm more familiar with the Pico micro from Raspberry Pi (RP2040), where they provide CMake integration for compiling a compatible binary, and it's otherwise just a C program using a simple library for GPIO access. Interesting virtual filesystem interface for flashing a program easily, although personally I build and use their open source utility because that can also write static data into spare memory locations.

I would start the other way around. Think of a problem and then how to use the arduino to solve it

https://hackaday.com/category/arduino-hacks/