https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289486/ "Conclusion: The results are very promising, but the therapy still requires maturation. Further studies are needed to systematize all the techniques used and their effects in order to enable use in humans."
$2 worth of electricity to fix old person syndrome. Watch this memory hole faster than Epsteins client list.
Five year old me was climbing on a gate to the horse pasture. I knew the hot wire was on but never really cared. Wintertime, I was playing in the snow and felt it was a good idea to climb on the gate. Holding on for a bit it felt like I was hit in the spine with a rock. Dumbfounded, looking around I realized I was electrocuted.
In my 20s I zapped my finger in a light socket trying to bend the bottom contact up...not knowing the switch was on.
The paper says the ultrasound and microbubbles are a way to briefly open the blood brain barrier to let more drugs through, nothing about breaking up the plaques. Still an interesting study
Based on what I read, this "study" is just a review and consolidation of other actual studies. They didn't do any science here. However, in the "Results" section of the abstract it does state "Fifteen original studies were selected. Preclinical trials were able to reduce amyloid-b plaques and tau phosphorylation, improving cognitive performance in AD animals."
Also, in the studies they consolidated there are several that mention in their results that it breaks up the plaques. For example: "Jordão et al., 201010 Mouse FUS associated with administration of anti-b-amyloid antibody (BAM 10) in transgenic mice (TgCRND8) promoted a significant reduction of b-amyloid peptide plaques."
Fair enough. On a different note, did you hear about how one of the biggest names in Alzheimer's research is getting investigated for potentially falsifying results of decades of studies? Crazy times we live in. But back to the point, it would be really cool if ultrasound becomes a useful treatment for dementia.
[ + ] Puller_of_Noses
[ - ] Puller_of_Noses 18 points 11 monthsMay 7, 2024 08:40:34 ago (+18/-0)
[ + ] fritz_maurentod
[ - ] fritz_maurentod 10 points 11 monthsMay 7, 2024 09:15:50 ago (+10/-0)
[ + ] Puller_of_Noses
[ - ] Puller_of_Noses 5 points 11 monthsMay 7, 2024 09:24:33 ago (+5/-0)
[ + ] Weredawg
[ - ] Weredawg 1 point 11 monthsMay 7, 2024 08:44:22 ago (+1/-0)
[ + ] Hobama
[ - ] Hobama 0 points 11 monthsMay 7, 2024 12:58:52 ago (+0/-0)
[ + ] Fishsticksforever
[ - ] Fishsticksforever 11 points 11 monthsMay 7, 2024 07:43:38 ago (+11/-0)
[ + ] 2plus2equals5
[ - ] 2plus2equals5 19 points 11 monthsMay 7, 2024 09:40:36 ago (+19/-0)
"Conclusion:
The results are very promising, but the therapy still requires maturation. Further studies are needed to systematize all the techniques used and their effects in order to enable use in humans."
$2 worth of electricity to fix old person syndrome. Watch this memory hole faster than Epsteins client list.
[ + ] dontbeaphaggot
[ - ] dontbeaphaggot 6 points 11 monthsMay 7, 2024 09:49:15 ago (+6/-0)
[ + ] Deleted
[ - ] deleted 0 points 11 monthsMay 7, 2024 18:37:33 ago (+0/-0)
[ + ] bobdole9
[ - ] bobdole9 10 points 11 monthsMay 7, 2024 08:09:00 ago (+10/-0)
[ + ] allAheadFull
[ - ] allAheadFull 5 points 11 monthsMay 7, 2024 13:09:17 ago (+5/-0)
https://www.medicalnewstoday.com/articles/alzheimers-study-controversy-what-does-it-mean-for-future-research#What-might-this-mean-for-dementia-research?
[ + ] bobdole9
[ - ] bobdole9 4 points 11 monthsMay 7, 2024 13:11:57 ago (+4/-0)
[ + ] Boyakasha
[ - ] Boyakasha 0 points 11 monthsMay 7, 2024 11:56:13 ago (+0/-0)
[ + ] Hobama
[ - ] Hobama 1 point 11 monthsMay 7, 2024 12:59:52 ago (+1/-0)
[ + ] GreenSaint
[ - ] GreenSaint 4 points 11 monthsMay 7, 2024 08:04:49 ago (+4/-0)
[ + ] Peleg
[ - ] Peleg 4 points 11 monthsMay 7, 2024 08:08:44 ago (+4/-0)
[ + ] Fascinus
[ - ] Fascinus 4 points 11 monthsMay 7, 2024 11:57:16 ago (+4/-0)
I saw the heroes in the cartoons getting all powered up and thought it looked pretty awesome.
I wanted to do that too and I knew where power came from. Let's do this!
Managed to wedge my pointer finger into the left slot and ZAP!
That shit HURT. All these years later, every time I smell ozone it takes me back to that moment.
[ + ] bobdole9
[ - ] bobdole9 3 points 11 monthsMay 7, 2024 13:16:25 ago (+3/-0)
In my 20s I zapped my finger in a light socket trying to bend the bottom contact up...not knowing the switch was on.
[ + ] paul_neri
[ - ] paul_neri 0 points 11 monthsMay 8, 2024 06:17:57 ago (+0/-0)
[ + ] TheNoticing
[ - ] TheNoticing 2 points 11 monthsMay 7, 2024 14:00:18 ago (+2/-0)
[ + ] Fascinus
[ - ] Fascinus 2 points 11 monthsMay 7, 2024 14:27:14 ago (+2/-0)
[ + ] noonefromnowhere
[ - ] noonefromnowhere 3 points 11 monthsMay 7, 2024 13:18:57 ago (+3/-0)
[ + ] sharkbait
[ - ] sharkbait 0 points 11 monthsMay 7, 2024 20:28:56 ago (+0/-0)
Also, in the studies they consolidated there are several that mention in their results that it breaks up the plaques. For example: "Jordão et al., 201010 Mouse FUS associated with administration of anti-b-amyloid antibody (BAM 10) in transgenic mice (TgCRND8) promoted a significant reduction of b-amyloid peptide plaques."
[ + ] noonefromnowhere
[ - ] noonefromnowhere 0 points 5 monthsNov 3, 2024 12:07:51 ago (+0/-0)
[ + ] TheNoticing
[ - ] TheNoticing 1 point 11 monthsMay 7, 2024 13:58:24 ago (+1/-0)
[ + ] mikenigger
[ - ] mikenigger 1 point 11 monthsMay 7, 2024 08:54:53 ago (+1/-0)
[ + ] paul_neri
[ - ] paul_neri 0 points 11 monthsMay 8, 2024 06:15:50 ago (+0/-0)
[ + ] Badgeroo
[ - ] Badgeroo 0 points 11 monthsMay 7, 2024 11:53:37 ago (+0/-0)
[ + ] Panic
[ - ] Panic 0 points 11 monthsMay 7, 2024 11:50:43 ago (+0/-0)