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Malwarebytes has gained significant popularity due to its specialized focus on detecting and removing malware, including emerging threats that traditional antivirus might miss. It has a strong user base among both individual consumers and businesses, often recommended for its effectiveness against ransomware and other complex threats.

HitmanPro is also well-regarded, particularly for its second-opinion scanning capability. It's often used by tech-savvy users or IT professionals who need an additional layer of security scanning to confirm the health of a system. HitmanPro's reputation for catching malware that other scanners miss has made it a popular choice for thorough system checks.

Emsisoft Emergency Kit: This is a free, portable tool that uses dual-engine scanning (Emsisoft and Bitdefender) to detect and remove malware. It's highly regarded for its effectiveness and is often used as a second-opinion scanner.

Zemana Anti-Malware: Known for its cloud-based scanning technology, Zemana can be used as a secondary scanner. It's particularly praised for its ability to remove rootkits, bootkits, and other persistent threats.

Kaspersky Virus Removal Tool: This is a free utility from Kaspersky that provides a powerful scan for malware. It's not a real-time protection tool but serves well for on-demand scanning, especially for stubborn threats.

Norton Power Eraser: Offered by Norton, this is a free tool designed to tackle tough malware that might have evaded regular antivirus programs. It's aggressive in its approach and can be used for a second opinion.

ESET Online Scanner: ESET provides a free, online-based scanner that works alongside your existing antivirus. It's known for its thorough malware detection capabilities.

Sophos Scan & Clean: Similar to HitmanPro, as it's now part of the Sophos suite, this tool provides effective malware scanning and removal, utilizing multiple antivirus engines.

AdwCleaner: While more focused on adware, PUPs (Potentially Unwanted Programs), and browser hijackers, it's an excellent tool for cleaning up specific types of unwanted software that might be missed by other scanners.

F-Secure Online Scanner: This is another free tool that can be used for a one-time scan to check for malware that might have evaded your primary antivirus.